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Clinical Trials Search

As a clinical trial candidate at Methodist, you’re offered unique access to new drugs and technology being studied to improve patient outcomes.
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Showing 1-10 results of 63
Sarcoma

(I.R.I.S.) Servier / CL3-95031-007

Official Title: A Phase 3, multicenter, double-blind, randomized, placebo-controlled study of ivosidenib in participants ≥18 years of age with locally advanced or metastatic conventional chondrosarcoma with an IDH1 mutation, untreated or previously treated with 1 systemic treatment regimen
Study Purpose: To assess how well the drug Ivosidenib works against chondrosarcoma
Status: Recruiting
Gynecologic Cancer

AFT-50

Official Title: A Phase IB/II Multi-cohort Study of Targeted Agents with Atezolizumab for Patients with Recurrent or Persistent Endometrial Cancer
Study Purpose: To evaluate the efficacy and safety of targeted agents plus cancer immune checkpoint therapy with atezolizumab for patients with recurrent and/or persistent endometrial cancer.
Status: Recruiting
Breast Cancer

Alliance / A011801

Official Title: T-DM1 and Tucatinib Compared With T-DM1 Alone In Preventing Relapses In People With High Risk Her2-Positive Breast Cancer
Study Purpose: To compare the usual treatment with T-DM1 alone to T-DM1 plus tucatinib.
Status: Recruiting
Breast Cancer

Alliance / A012103

Official Title: OptimICE-PCR: De-Escalation of Therapy in Early-Stage TNBC Patients Who Achieve pCR After Neoadjuvant Chemotherapy with Checkpoint Inhibitor Therapy  
Study Purpose: To evaluate whether observation results in a non-inferior recurrence free survival compared to adjuvant pembrolizumab in early-stage TNBC patients who achieve a pathological complete response after neoadjuvant chemotherapy with pembrolizumab 
Status: Recruiting
Gastrointestinal Cancer

Alliance / A021806

Official Title: Testing The Use Of The Usual Chemotherapy Before And After Surgery For Removable Pancreatic Cancer
Study Purpose: To determine if receiving chemotherapy before and after surgery will increase the chance of pancreatic cancer staying away.
Status: Recruiting
Gastrointestinal Cancer

Alliance / A022106

Official Title: PHASE II/III SECOND-LINE NABPLAGEM VS. NAB-PACLITAXEL/GEMCITABINE IN BRCA1/2 OR PALB2 MUTANT METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA (PLATINUM)
Study Purpose: To evaluate and compare overall response rate (ORR) in patients with BRCA1/2 or PALB2 mutant pancreas cancer whose disease has progressed on front-line FOLFIRINOX treated with NABPLAGEM = nab-paclitaxel, gemcitabine, and cisplatin (arm 1) versus nab-paclitaxel and gemcitabine (arm 2)
Status: Recruiting
Urinary Cancer

Alliance / A031702

Official Title: Testing the effectiveness of two immunotherapy drugs (nivolumab and ipilimumab) with one anti-cancer targeted drug (cabozantinib) for rare genitourinary tumors
Study Purpose: To test the good and bad effects of the drugs cabozantinib, nivolumab, and ipilimumab in rare genitourinary cancers that have no standard treatment options.The doctors hope to learn if the study drugs will stabilize or shrink the cancer.
Status: Recruiting
Brain Cancer Other Trials

Alliance / A071702

Official Title: A Phase II Study of Checkpoint Blockade Immunotherapy in Patients with Somatically Hypermutated Recurrent WHO Grade 4 Glioma 
Study Purpose: To determine whether the combination of ipilimumab and nivolumab increases the tumor response rate in patients with hypermutated recurrent glioblastoma
Status: Suspended
Lung Cancer

Alliance / A081801

Official Title: Testing The Addition Of A Type Of Drug Called Immunotherapy To The Usual Chemotherapy Treatment For Non-Small Cell Lung Cancer
Study Purpose: To compare the usual treatment alone to using pembrolizumab plus the usual treatment.  The addition of pembrolizumab to the usual treatment could prevent it from returning.
Status: Recruiting
Lung Cancer

Alliance / A092001

Official Title: PHASE 2 RANDOMIZED TRIAL OF NEOADJUVANT OR PALLIATIVE CHEMOTHERAPY WITH OR WITHOUT IMMUNOTHERAPY FOR PERITONEAL MESOTHELIOMA
Study Purpose: To determine whether frontline treatment with carboplatin, pemetrexed, bevacizumab and atezolizumab results in a superior best response rate than carboplatin, pemetrexed and bevacizumab in patients with peritoneal mesothelioma
Status: Available