Genentech BO45217
Trial Overview
Official Title
Phase III Randomized, Open-label, Multicenter Study Evaluating the Efficacy and Safety of Divarasib versus Sotorasib or Divarasib in patients with previously treated KRAS G12C-positive Advanced or Metastatic NSCLC
Study Purpose
To evaluate the effectiveness of divarasib compared to currently approved Sotorasib or Adagrasib
Diagnosis
Non-small cell lung cancer (NSCL) that is KRAS G12 C + If KRAS is unknown, study will test.Eligibility
Unresectable stage IIIC or IV that has progressed during or after at least one prior treatment regimen.
Intervention
Experimental arm: Divarasib
Control arm: Sotorasib or Adagrasib
For more information visit
Clinicaltrials.gov
Key Participation Requirements
Trial Location(s)
Gender
Male or Female
Age
18 years and Older
Enrollment Status
Pending
Phase
Phase III