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Aadi TSC-007

Trial Overview

Official Title

A phase 2 multi-center open label basket trial of nab-sirolimus for adult and adolescent patients with malignant solid tumors harboring pathogenic inactivating alterations in TSC1 or TSC2 genes

Study Purpose

To find out more about the safety and effectiveness of nab-sirolimus in adolescents and adults with advanced solid tumors bearing TSC1 or TSC2 inactivating mutation

Diagnosis

Malignant solid tumors that are metastatic or locally advanced and have a pathogenic inactivating TSC1 or TSC2 alteration

Eligibility

Surgical resection is not an option and standard therapies have not been effective

Intervention

nab-Sirolimus

For more information, visit Clinicaltrials.gov

Key Participation Requirements
Trial Location(s)
Methodist Estabrook Cancer Center
Gender
Male or Female
Age
12 years and older
Enrollment Status
Recruiting
Phase
Phase II
Methodist Health System Trial Code
Aadi TSC-007