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Clinical Trials Search

As a clinical trial candidate at Methodist, you’re offered unique access to new drugs and technology being studied to improve patient outcomes.
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Showing 61-70 results of 79
Gynecologic Cancer

NRG-GY026

Official Title: Testing the addition of Herceptin Hylecta or Phesgo to the usual chemotherapy for HER2 positive endometrial serous carcinoma or carcinosarcoma.
Study Purpose: To determine if the addition of the study drugs will lower the chance of this disease from coming back.
Status: Recruiting
Gynecologic Cancer

NRG-GY033

Official Title: A PHASE II STUDY OF ANDROGEN RECEPTOR (AR) INHIBITION BY DAROLUTAMIDE IN COMBINATION WITH LEUPROLIDE ACETATE AND EXEMESTANE IN RECURRENT ADULT-TYPE OVARIAN GRANULOSA CELL TUMOR
Study Purpose: To test the effectiveness and the good and bad effects of the drug darolutamide in combination with leuprolide acetate and exemestane 
Status: Recruiting
Head and Neck Cancer

NRG-HN010

Official Title: Testing the use of ado-trastuzumab emtansine compared to the usual treatment (chemotherapy with docetaxel plus trastuzumab) for recurrent, metastatic, or unresectable HER2-Positive salivary gland cancer.
Study Purpose: Will ado-trastuzumab emtansine extend the length of time without your cancer getting worse compared to standard of care?
Status: Recruiting
Lung Cancer

NRG-LU008

Official Title: Phase III Prospective Randomized Trial of Primary Lung Tumor Stereotactic Body Radiation Therapy Followed By Concurrent Mediastinal Chemoradiation For Locally Advanced Non-Small Cell Lung Cancer 
Study Purpose: To compare overall survival in patients with Stage II-IIIC inoperable Non-small cell lung cancer comparing conventional radiation with chemotherapy  to stereotactic body radiation and conventional  radiation along with chemotherapy
Status: Recruiting
Pulmonology

PASSAGE

Official Title: A Multicenter, Single-arm, Open-label, Post-Authorization, Phase 4 Effectiveness and Safety Study of Tezepelumab in Adult and Adolescent Participants With Severe Asthma Including Several Under-Studied Populations in the United States (PASSAGE)
Study Purpose: To assess the effectiveness of tezepelumab in the United States (US) among a real-world population of adults participants with asthma requiring medium-dose to high-dose inhaled corticosteroids (ICS)
Status: Recruiting
Breast Cancer

Personalis 01-PS-001

Official Title: Breast Cancer-Minimal/Molecular Residual Disease Detection and Therapy Monitoring in Patients with Early Stage TNBC-Phase I (B-STRONGER-I)
Study Purpose: Evaluate the correlation of Minimal Residual Disease detection by NeXT Personal CTA (a molecular test) to pathological Complete Response (pCR) after neoadjuvant chemotherapy (NAC) in stage I-III triple negative breast cancer (TNBC)
Status: Recruiting
Heart and Vascular

PIVoTAL-IDE

Official Title: Left Atrial Posterior Wall Isolation in Conjunction with Pulmonary Vein Isolation Using the Cryoballoon for Treatment of Persistent Atrial Fibrillation (PIVoTAL-IDE) Trial
Study Purpose: To compare cryoballoon ablation with posterior wall isolation to cryoballoon ablation in the treatment of persistent atrial fibrillation and the efficacy over a 12 month time span.
Status: Active, Not Recruiting
Skin Cancer

Regeneron R2810-ONC-1788

Official Title: A Randomized, Placebo-Controlled, Double-Blind Study of Adjuvant Cemiplimab Versus Placebo after Surgery and Radiation Therapy in Patients with High Risk Cutaneous Squamous Cell Carcinoma (CSCC)
Study Purpose: To determine if cemiplimab will prevent CSCC from returning after surgery and radiation. The researchers also want to find out if cemiplimab will help people live longer, how study participation affects how people feel, and side effects that people may experience during the study.
Status: Recruiting
Heart and Vascular

ROMA WOMEN

Official Title: Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts: the ROMA trial
Study Purpose: It is the first cardiac surgery trial dedicated exclusively to women. Patients will be randomized in a 1:1 fashion. Patients will be randomized to a single arterial graft (SAG) or multiple arterial grafts (MAG).
Status: Recruiting
Lung Cancer

S1914

Official Title: A randomized Phase III Trial of Induction/consolidation Atezolizumab (NSC #783608) + SBRT Alone in High Risk, Early Stage NSCL
Study Purpose: To compare overall survival in patients with inoperable, early stage non-small cell lung cancer (NSCLC) randomized to stereotactic body radiation therapy (SBRT) with or without atezolizumab
Status: Recruiting