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Clinical Trials Search

As a clinical trial candidate at Methodist, you’re offered unique access to new drugs and technology being studied to improve patient outcomes.
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Showing 1-9 results of 9
Breast Cancer

AFT-38

Official Title: Randomized, Open Label, Clinical Study of the Targeted Therapy, Palbociclib, to Treat Metastatic Breast Cancer (PATINA)
Study Purpose: To determine if adding palbociclib to standard treatment with anti-HER2-based therapy plus endocrine therapy is more effective in preventing cancer from getting worse.
Status: Recruiting
Breast Cancer

Alliance A011801

Official Title: T-DM1 and Tucatinib Compared With T-DM1 Alone In Preventing Relapses In People With High Risk Her2-Positive Breast Cancer
Study Purpose: To compare the usual treatment with T-DM1 alone to T-DM1 plus tucatinib.
Status: Recruiting
Breast Cancer

Alliance A221505

Official Title: Phase III Randomized Trial of Hypo-fractionated Post Mastectomy Radiation with Breast Reconstruction
Study Purpose: To determine if a shorter course of radiation therapy (3-4 weeks) is as safe and effective as the typical 5 to 6 week treatment course after mastectomy.
Status: Recruiting
Breast Cancer

ECOG-ACRIN EA1131

Official Title: Testing Platinum-Based Chemotherapy After Surgery In Triple-Negative Breast Cancers
Study Purpose: To determine if getting more treatment with capecitabine to any good and bad effects of getting more treatment with cisplatin or carboplatin after surgery. The results of this study will provide knowledge as to what approach is better, the same or worse than using capecitabine chemotherapy.
Status: Recruiting
Breast Cancer

NRG BR003

Official Title: A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer
Study Purpose: To compare the good and bad effects of the chemotherapy drug, carboplatin, given with the usual chemotherapy drugs after surgery, compared to the usual chemotherapy drugs given without carboplatin.
Status: Recruiting
Breast Cancer

NRG BR004

Official Title: Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer
Study Purpose: To study how well paclitaxel, trastuzumab and pertuzumab with or without atezolizumab works in treating patients with breast cancer that has spread to other parts of the body. (metastatic)
Status: Recruiting
Breast Cancer

SWOG S1418

Official Title: Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer
Study Purpose: To determine if adding pembrolizumab to the standard treatment for triple negative breast cancer, decreases the risk of the cancer returning (after receiving standard chemotherapy and/or radiation).
Status: Suspended
Breast Cancer

SWOG S1706

Official Title: A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently with Radiotherapy versus Radiotherapy Alone for Inflammatory Breast Cancer
Study Purpose: To determine if adding the drug olaparib to the usual radiation therapy for inflammatory breast cancer will decrease the risk of cancer returning.
Status: Recruiting
Breast Cancer

UNMC SPARCC

Official Title: Study on Physical Activity’s Relationship with Cancer and Cognition (SPARCC): A Pilot Randomized Trial
Study Purpose: To evaluate a physical activity program designed to develop additional programs aimed at improving quality of life in women with breast cancer. The study is trying to determine the effect of an aerobic exercise walking program on cognition in breast cancer survivors.
Status: Recruiting