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NRG / LU008

Trial Overview

Official Title

Phase III Prospective Randomized Trial of Primary Lung Tumor Stereotactic Body Radiation Therapy Followed By Concurrent Mediastinal Chemoradiation For Locally Advanced Non-Small Cell Lung Cancer

 

Study Purpose

To compare overall survival in patients with Stage II-IIIC inoperable Non-small cell lung cancer comparing conventional radiation with chemotherapy  to stereotactic body radiation and conventional  radiation along with chemotherapy

Diagnosis

Stage II OR III non-small cell lung cancer with known tumor marker (PDL-1)

Eligibility

Locally advanced, inoperable node positive non small cell lung cancer.  Deemed appropriate for curative intent.  No distant metastases.

Intervention

:  Arm 1--conventional radiation to the primary tumor and/or  metastases given with chemotherapy (OR)

                          Arm 2-- stereotactic body radiation (SBRT) to the primary tumor followed by conventional radiation with chemotherapy.

For more information, click the link below:

 

https://clinicaltrials.gov/study/NCT05624996?term=LU008&rank=1

 

Key Participation Requirements
Gender
Male or Female
Age
19 years and older
Enrollment Status
Recruiting
Phase
Phase III
Methodist Health System Trial Code
LU008