For COVID-19 and vaccination updates, view our information for the community. If you're experiencing symptoms, call your primary care provider.

Notice of Blackbaud Incident.

Decorative dot pattern background image.
Decorative blue shape background image. Decorative blue shape background image. Decorative blue shape background image. Decorative blue shape background image.

Clinical Trials Search

As a clinical trial candidate at Methodist, you’re offered unique access to new drugs and technology being studied to improve patient outcomes.
Filter by Disease or Condition
Showing 1-10 results of 102
Head and Neck Cancer

AbbVie M19-894

Official Title: A Phase 1B, Multicenter, Open-Label Study To Determine The Safety, Tolerability, Pharmacokinetics, And Preliminary Efficacy Of Abbv-368 Plus Tilsotolimod And Other Therapy Combinations In Subjects With Recurrent/Metastatic Head And Neck Squamous Cell Carcinoma
Study Purpose: This study will evaluate the effect the combination therapies have on the patient’s body and evaluate the tumor activity and use biomarker tests and imaging results to determine the effects of the combination therapy the patients are assigned to.
Status: Recruiting
Cardiology

ADVENT-IDE

Official Title: A Prospective Randomized Pivotal Trial of the FARAPULSE Pulsed Field Ablation System Compared With Standard of Care Ablation in Patients With Paroxysmal Atrial Fibrillation
Study Purpose: This is a prospective, adaptive, multi-center, randomized safety and effectiveness pivotal study comparing the FARAPULSE Pulsed Field Ablation System with standard of care ablation with force-sensing RF catheters and cryoballoon catheters indicated for the treatment of PAF.
Status: Pending
Urinary Cancer

AFT-19

Official Title: A Phase 3 Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer
Study Purpose: To compare progression free survival and overall survival of the standard hormone therapy degarelix verses  degarelix and apalutamide versus degarelix, apalutamide, abiraterone, and prednisone.
Status: Recruiting
Breast Cancer

AFT-38

Official Title: Randomized, Open Label, Clinical Study of the Targeted Therapy, Palbociclib, to Treat Metastatic Breast Cancer (PATINA)
Study Purpose: To determine if adding palbociclib to standard treatment with anti-HER2-based therapy plus endocrine therapy is more effective in preventing cancer from getting worse.
Status: Recruiting
Breast Cancer

Alliance A011801

Official Title: T-DM1 and Tucatinib Compared With T-DM1 Alone In Preventing Relapses In People With High Risk Her2-Positive Breast Cancer
Study Purpose: To compare the usual treatment with T-DM1 alone to T-DM1 plus tucatinib.
Status: Recruiting
Gastrointestinal Cancer

Alliance A021502

Official Title: Testing the Addition of the Antibody Atezolizumab to Usual Chemotherapy after Surgery in Patients with Colon Cancer
Study Purpose: To compare any good and bad effects of using the drug atezolizumab along with the usual chemotherapy compared to the usual chemotherapy alone.
Status: Recruiting
Gastrointestinal Cancer

Alliance A021602

Official Title: Testing cabozantinib in patients with advanced pancreatic neuroendocrine and carcinoid tumors after progression on everolimus
Study Purpose: The purpose of this study is to learn if treatment with a drug called cabozantinib to prevent tumor growth is better, the same, or worse than placebo (a pill that contains no active drug).
Status: Recruiting
Gastrointestinal Cancer

Alliance A021703

Official Title: Randomized Double-Blind Phase III Trial of Vitamin D3 Supplementation in Patients With Previously Untreated Metastatic Colorectal Cancer (Solaris)
Study Purpose: To compare amount of time until the cancer advances in patients receiving high-dose vitamin D3 in combination with standard chemotherapy (FOLFOX or FOLFIRI) and bevacizumab against patients receiving standard-dose vitamin D3 in combination with standard chemotherapy and bevacizumab.
Status: Recruiting
Gastrointestinal Cancer

Alliance A021806

Official Title: Testing The Use Of The Usual Chemotherapy Before And After Surgery For Removable Pancreatic Cancer
Study Purpose: To determine if receiving chemotherapy before and after surgery will increase the chance of pancreatic cancer staying away.
Status: Recruiting
Urinary Cancer

Alliance A031102

Official Title: A Randomized Phase III Trial Comparing Conventional-Dose Chemotherapy Using Paclitaxel, Ifosfamide, and Cisplatin (TIP) With High-Dose Chemotherapy Using Mobilizing Paclitaxel Plus Ifosfamide Followed by High-Dose Carboplatin and Etoposide (TI-CE) as First Salvage Treatment in Relapsed or Refractory Germ Cell Tumors
Study Purpose: To determine if giving high dose chemotherapy and having a stem cell transplant will prevent or lengthen the time the time to recurrence when compared to the usual treatment of chemotherapy.  
Status: Recruiting