Clinical Trials Search

Official Title: BOLT: A Prospective, Multicenter Study of Patients with Deep Vein Thrombosis to Evaluate the Safety and Efficacy of the Indigo® Aspiration System

Study Purpose: Evaluated Safety and Efficacy of Indigo Aspiration System

Status: Recruiting

Official Title: Integrated Cancer Repository for Cancer Research (iCaRe2) – Breast Cancer Collaborative Repository

Study Purpose: This registry/tissue bank focuses on the collection of detailed information and biological samples to help create a resource that will be helpful to cancer researchers to study risk factors for a number of different types of cancer and other diseases, which relate to cancer.

Status: Recruiting

Official Title: Brightline-4: A Phase III open-label, single-arm, multi-center study to assess the safety and efficacy of brigimadlin (BI 907828) treatment in patients with treatment-naïve or pre-treated advanced dedifferentiated liposarcoma 

Study Purpose: The primary objective is to evaluate the safety of brigimadlin in patients with advanced or metastatic DDLPSThe secondary objectives are to evaluate efficacy by using objective response (OR), duration of objective response (DOR), PFS, and overall survival (OS), and to further assess safety.

Status: Recruiting

Official Title: A PHASE 3 RANDOMIZED, OPEN-LABEL, MULTICENTER CLINICAL STUDY OF CGT9486+SUNITINIB VS SUNITINIB IN SUBJECTS WITH LOCALLY ADVANCED, UNRESECTABLE OR METASTATIC GASTROINTESTINAL STROMAL TUMORS 

Study Purpose: The purpose of this part of the research study is to evaluate how CGT9486 plus sunitinib affects GIST compared to just treatment with sunitinib alone. 

Status: Recruiting

Official Title: The CHRONICLE Study: A Longitudinal Prospective Observational Study of the Characteristics, Treatment Patterns and Health Outcomes of Individuals With Severe Asthma in the United States

Study Purpose: The CHRONICLE Study is a multi-center, non-interventional, prospective cohort study of adults with severe asthma who do not achieve control with high-dose inhaled corticosteroid (ICS) therapy with additional controllers and/or require systemic corticosteroid or monoclonal antibody therapy. Data will be collected from the healthcare provider in a uniform manner for every patient enrolled using an electronic case report form (eCRF). Data will be collected monthly from patients via web-based surveys. Patients will be followed until study discontinuation or the patient withdraws from the study or death, whichever occurs first. The expectation is that patients will be followed for a period of at least 3 years.

Status: Recruiting

Official Title: Center for International Blood and Marrow Transplant Research: Protocol for a Research Database for Hematopoietic Cell Transplantation and Cellular Therapies

Study Purpose: To gather health information from patients receiving stem cell transplants that can be used to find ways to make stem cell transplants work better. 

Status: Recruiting

Official Title: A Phase 3, multicenter, double-blind, randomized, placebo-controlled study of ivosidenib in participants ≥18 years of age with locally advanced or metastatic conventional chondrosarcoma with an IDH1 mutation, untreated or previously treated with 1 systemic treatment regimen

Study Purpose: To assess how well the drug Ivosidenib works against chondrosarcoma

Status: Pending

Official Title: A Phase II, Single-Arm Study of Giredestrant in Patients with Grade 1 Endometrial Cancer

Study Purpose: To assess the efficacy, safety, and pharmacokinetics of giredestrant in participants with Grade 1 endometrioid endometrial carcinoma.

Status: Recruiting

Official Title: A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Placebo for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein

Study Purpose: To compare any good and bad effects of using the study drug, crizotinib, after completion of surgery and, in some cases, after chemotherapy and/or radiation therapy for ALK-positive non-small cell lung cancer.

Status: Recruiting

Official Title: Targeted Treatment for Advanced Non-small Cell Lung Cancer

Study Purpose: To find out if a targeted or immunotherapy treatment will have an effect on specific genes and proteins in the tumor.

Status: Recruiting