Clinical Trials Search

As a clinical trial candidate at Methodist, you’re offered unique access to new drugs and technology being studied to improve patient outcomes.
Filter by Disease or Condition
Showing 21-30 results of 46
Gynecologic Cancer

Gradalis / CL-PTL-135

Official Title: Blood and Tissue Procurement Protocol for Product Development and Research
Study Purpose: To collect cancerous tissue/fluid and blood samples to store and use for research purposes.
Status: Recruiting
Cardiovascular

InnaVasc

Official Title: Clinical Trial Title    A Study to Evaluate the Safety and Effectiveness of the InnaVasc Arteriovenous Graft for Hemodialysis Access in Patients with End-Stage Renal Disease (InnaVasc)
Study Purpose: This clinical trial is a prospective, multi-center, single-arm study designed to assess the safety and effectiveness of the IG device in subjects with ESRD who require hemodialysis.
Status: Recruiting
Sarcoma

Intensity Therapeutics / IT-03

Official Title: A Multicenter, Randomized, Phase III Study to Assess the Efficacy and Safety of INtratumorally Administered INT230-6 (SHAO, VINblastine, CIsplatin) Compared With Standard of Care in Adult participants With Locally Recurrent, InoperaBLE, or Metastatic Soft Tissue Sarcomas - (THE INVINCIBLE-3 TRIAL) 
Study Purpose: To evaluate the effectiveness of IT-03 compared to the usual treatment of pazopanib, trabectedin or eribulin 
Status: Suspended
Cardiovascular

LeAAPS

Official Title: Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction (LeAAPS) Trial
Study Purpose: To evaluated safety and effectiveness of prophylactic LAAE for the prevention of ischemic stroke or systemic embolism in subjects undergoing cardiac surgery who have risk factors for AF and ischemic stroke
Status: Active, Not Recruiting
Gynecologic Cancer

NRG / CC008

Official Title: A Non-Randomized Prospective Clinical Trial Comparing the Non-Inferiority of Salpingectomy to Salpingo-oophorectomy to Reduce the Risk of Ovarian Cancer Among BRCA1 Carriers [SOROCk]
Study Purpose: The purpose of the study is to compare two surgical procedures and their ability to decrease the risk of developing ovarian cancer for pre-menopausal women with BRCA1 mutations.
Status: Recruiting
Gynecologic Cancer

NRG / GY024

Official Title: Groningen International Study on Sentinel Nodes in Vulvar Cancer (GROINSS-V) III: A Prospective Phase II Treatment Trial  
Study Purpose: To investigate the safety of replacing inguinofemoral lymphadenectomy by chemoradiation in early stage vulvar cancer patients with a macrometastasis and/or extracapsular extension in the SN.
Status: Recruiting
Gynecologic Cancer

NRG / GY026

Official Title: Testing the addition of Herceptin Hylecta or Phesgo to the usual chemotherapy for HER2 positive endometrial serous carcinoma or carcinosarcoma.
Study Purpose: To determine if the addition of the study drugs will lower the chance of this disease from coming back.
Status: Recruiting
Gynecologic Cancer

NRG / GY035

Official Title: A Randomized Phase III Trial of Carboplatin, Paclitaxel, and Pembrolizumab versus Carboplatin, Paclitaxel, and Bevacizumab versus Carboplatin, Paclitaxel, Pembrolizumab and Bevacizumab in the Treatment of PMMR, TP53 Mutated Advanced or Recurrent Endometrial Cancer
Study Purpose: To find out if adding a drug that blocks cancer blood vessel growth (bevacizumab) to the usual approach of paclitaxel and carboplatin with or without pembrolizumab immunotherapy lowers the chance of endometrial cancer growing or spreading.
Status: Recruiting
Head and Neck Cancer

NRG / HN006

Official Title: Randomized Phase II/III Trial of Sentinel Lymph Node Biopsy Versus Elective Neck Dissection for Early-Stage Oral Cavity CancerRandomized Phase II/III Trial of Sentinel Lymph Node Biopsy Versus Elective Neck Dissection for Early-Stage Oral Cavity Cancer
Study Purpose: To see if neck and shoulder function and pain are better after SLN biopsy surgery compared to the usual approach and to see if SLN biopsy surgery is as good as the usual approach in extending your time without cancer.
Status: Recruiting
Head and Neck Cancer

NRG / HN010

Official Title: Testing the use of ado-trastuzumab emtansine compared to the usual treatment (chemotherapy with docetaxel plus trastuzumab) for recurrent, metastatic, or unresectable HER2-Positive salivary gland cancer.
Study Purpose: Will ado-trastuzumab emtansine extend the length of time without your cancer getting worse compared to standard of care?
Status: Recruiting