For COVID-19 and vaccination updates, view our information for the community. If you're experiencing symptoms, call your primary care provider.

Decorative dot pattern background image.
Decorative blue shape background image. Decorative blue shape background image. Decorative blue shape background image. Decorative blue shape background image.

Clinical Trials Search

As a clinical trial candidate at Methodist, you’re offered unique access to new drugs and technology being studied to improve patient outcomes.
Filter by Disease or Condition
Showing 1-10 results of 12
Gynecologic Cancer

GOG-0263

Official Title: Randomized Phase III Clinical Trial of Adjuvant Radiation Versus Chemoradiation in Intermediate Risk, Stage I/IIA Cervical Cancer Treated With Initial Radical Hysterectomy and Pelvic Lymphadenectomy
Study Purpose: To determine if adding chemotherapy to radiation therapy (CRT) can prevent or lengthen the time to recurrence when compared to radiation therapy (RT) alone.
Status: Recruiting
Gynecologic Cancer

GOG-3029/ENGOT-ov50/INNOVATE-3, EF-28

Official Title: Pivotal, Randomized, Open-Label Study Of Tumor Treating Fields (TTFields, 200khz) Concomitant With Weekly Paclitaxel For The Treatment Of Recurrent Ovarian Cancer
Study Purpose: To compare treatment using TTFields together with standard of care chemotherapy (called Paclitaxel) to standard of care chemotherapy (Paclitaxel) without TTFields. This study will help determine if using TTFields with chemotherapy is better than the usual approach of chemotherapy alone.
Status: Recruiting
Gynecologic Cancer

Gradalis CL-PTL-135

Official Title: Blood and Tissue Procurement Protocol for Product Development and Research
Study Purpose: To collect cancerous tissue/fluid and blood samples to store and use for research purposes.
Status: Pending
Gynecologic Cancer

InterVenn OVACA-001

Official Title: Clinical Validation of the InterVenn Ovarian Cancer Liquid Biopsy: VOCAL Study
Study Purpose: To evaluate the clinical performance for the InterVenn Ovarian Cancer Liquid Biopsy by collecting and storing blood samples and characterizing protein biomarkers in the blood of cancer vs. non-cancer patients.
Status: Recruiting
Gynecologic Cancer

Merck MK7339-001/GOG-3036

Official Title: First-Line Chemotherapy Plus Pembrolizumab and Olaparib for BRCA Non-Mutated Advanced Epithelial Ovarian Cancer (EOC)
Study Purpose: To test the safety of the study drug, pembrolizumab (MK- 3475) with chemotherapy followed by olaparib OR pembrolizumab with chemotherapy compared to chemotherapy alone to see how well the drugs work and to see how your body handles them.
Status: Recruiting
Gynecologic Cancer

NRG CC008

Official Title: A Non-Randomized Prospective Clinical Trial Comparing the Non-Inferiority of Salpingectomy to Salpingo-oophorectomy to Reduce the Risk of Ovarian Cancer Among BRCA1 Carriers [SOROCk]
Study Purpose: The purpose of the study is to compare two surgical procedures and their ability to decrease the risk of developing ovarian cancer for pre-menopausal women with BRCA1 mutations.
Status: Recruiting
Gynecologic Cancer

NRG GY009

Official Title: A Randomized, Phase II/III Study Of Pegylated Liposomal Doxorubicin And Ctep-Supplied Atezolizumab (Ind #134427) Versus Pegylated Liposomal Doxorubicin/Bevacizumab And Ctep-Supplied Atezolizumab Versus Pegylated Liposomal Doxorubicin/Bevacizumab In Platinum Resistant Ovarian Cancer
Study Purpose: To compare any good and bad effects of adding Atezolizumab to the usual chemotherapy, (liposomal doxorubicin) and to the usual chemotherapy with bevacizumab.
Status: Suspended
Gynecologic Cancer

NRG GY014

Official Title: A phase II study of tazemetostat (EPZ-6438) (IND#138671) in recurrent or persistent endometrioid or clear cell carcinoma of the ovary, and recurrent or persistent endometrioid endometrial adenocarcinoma
Study Purpose: To find out if this approach is better or worse than the usual approach for your ovarian or endometrial cancer. 
Status: Suspended
Gynecologic Cancer

NRG GY018

Official Title: Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Endometrial Cancer.
Study Purpose: The purpose of this study is to compare any good and bad effects of adding immunotherapy drugs to the usual combination of chemotherapy drugs.
Status: Recruiting
Gynecologic Cancer

NRG GY019

Official Title: A Randomized Phase III, Two-Arm Trial of Paclitaxel/Carboplatin/Maintenance Letrozole versus Letrozole Monotherapy in Patients with Stage II-IV, Primary Low-Grade Serous Carcinoma of the Ovary or Peritoneum
Study Purpose: To determine how well the oral drug Letrozole works with or without Paclitaxel and Carboplatin in treating stage II-IV low grade cancer of the ovary or peritoneum.
Status: Recruiting