SWOG S1802

Official Title

Comparing the Treatment Outcome of Standard Systemic Therapy Only versus Standard Systemic Therapy in Combination with Either Surgery or Radiation Therapy, for Patients with Advanced Prostate Cancer

Study Purpose

To compare the effects, good and/or bad, of adding prostate removal surgery or radiation therapy to standard therapy which is used to treat prostate cancer.

Diagnosis

Eligibility

Must have an intact prostate.

No prior therapy for prostate cancer is allowed.

Must have cancer that has spread confirmed on a bone scan and CT or MRI.

Not eligible if cancer that has spread to the brain.

May have received no more than 28 weeks of prior standard systemic therapy.

Must not have progressed while on standard systemic therapy.

Patients must sign an approved informed consent and authorization permitting release of personal health information.

Intervention

• Standard Therapy (Androgen Deprivation Therapy with or without Chemotherapy)
• Surgery
• Radiation Therapy
• Quality of Life Questionnaires
• Group 1:  Standard Therapy
• Group 2:  Standard Therapy + Surgery or Radiation Therapy