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Breast Cancer

Breast Cancer

Alliance A011801

Official Title: T-DM1 and Tucatinib Compared With T-DM1 Alone In Preventing Relapses In People With High Risk Her2-Positive Breast Cancer
Study Purpose: To compare the usual treatment with T-DM1 alone to T-DM1 plus tucatinib.
Status: Recruiting
Breast Cancer

MacroGenics CP-MGC018-01

Official Title: A Phase 1/2, First-In-Human, Open-Label, Dose-Escalation Study Of MGC018 (Anti–B7-H3 Antibody Drug Conjugate) Alone And In Combination With Mga012 (Anti–PD-1 Antibody) In Patients With Advanced Solid Tumors
Study Purpose: To evaluate the safety and effectiveness of the test drug, MGC018.
Status: Recruiting
Breast Cancer

NRG BR003

Official Title: A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel with or without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast Cancer
Study Purpose: To compare the good and bad effects of the chemotherapy drug, carboplatin, given with the usual chemotherapy drugs after surgery, compared to the usual chemotherapy drugs given without carboplatin.
Status: Recruiting
Breast Cancer

NRG BR004

Official Title: Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer
Study Purpose: To study how well paclitaxel, trastuzumab and pertuzumab with or without atezolizumab works in treating patients with breast cancer that has spread to other parts of the body. (metastatic)
Status: Recruiting
Breast Cancer

SWOG S1706

Official Title: A Phase II Randomized Trial of Olaparib (NSC-747856) Administered Concurrently with Radiotherapy versus Radiotherapy Alone for Inflammatory Breast Cancer
Study Purpose: To determine if adding the drug olaparib to the usual radiation therapy for inflammatory breast cancer will decrease the risk of cancer returning.
Status: Recruiting
Breast Cancer

UNMC PACT

Official Title: The Patterns of Activity and Cognition during Treatment (PACT) Study
Study Purpose: To test a smartphone app in women receiving chemotherapy for breast cancer.
Status: Available