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Skin Cancer

Skin Cancer

Alliance A091802

Official Title: Avelumab With or Without Cetuximab in Treating Patients With Advanced Skin Squamous Cell Cancer
Study Purpose: To test the good and bad effects of the combined treatment, using the drugs cetuximab and avelumab as well as avelumab by itself.
Status: Recruiting
Skin Cancer

ECOG-ACRIN EA6141

Official Title: Randomized phase II/III study of nivolumab plus ipilimumab plus sargramostim versus nivolumab plus ipilimumab in patients with unresectable stage III or stage IV melanoma
Study Purpose: To compare any good and bad effects of giving three drugs- ipilimumab, nivolumab, and sargramostim at the same time compared to just ipilimumab and nivolumab together.
Status: Recruiting
Skin Cancer

ECOG-ACRIN EA6174

Official Title: Testing Pembrolizumab versus Observation in Patients with Merkel Cell Carcinoma after Surgery
Study Purpose: To see if the chance of cancer growing back can be lowered by adding the study drug, pembrolizumab, after surgery.
Status: Recruiting
Skin Cancer

Nektar Therapeutics 20-214-29/CA045-022/PIVOT12

Official Title: A Phase 3, Randomized, Open-Label Study To Compare Adjuvant Immunotherapy Of Bempegaldesleukin Combined With Nivolumab Versus Nivolumab After Complete Resection Of Melanoma In Patients At High Risk For Recurrence (Pivot 12)
Study Purpose: To compare the efficacy of bempegaldesleukin plus nivolumab versus nivolumab in patients with completely resected Stage IIIA cutaneous melanoma with no evidence of disease who are at high risk for recurrence.
Status: Recruiting
Skin Cancer

Regeneron R2810-ONC-1788

Official Title: A Randomized, Placebo-Controlled, Double-Blind Study of Adjuvant Cemiplimab Versus Placebo after Surgery and Radiation Therapy in Patients with High Risk Cutaneous Squamous Cell Carcinoma (CSCC)
Study Purpose: To determine if cemiplimab will prevent CSCC from returning after surgery and radiation. The researchers also want to find out if cemiplimab will help people live longer, how study participation affects how people feel, and side effects that people may experience during the study.
Status: Recruiting
Skin Cancer

SWOG S1801

Official Title: A phase II randomized study of adjuvant vs. neoadjuvant MK-3475 (Pembrolizumab) for clinically detectable stage III-IV high-risk melanoma
Study Purpose: To compare outcomes of receiving the study drug either before and after or only after surgery.
Status: Recruiting