Sarcoma

Official Title: Testing The Addition Of Nivolumab To Chemotherapy In Treatment Of Soft Tissue Sarcoma

Study Purpose: To compare treatment with chemotherapy (paclitaxel) alone to using a combination of nivolumab plus chemotherapy (paclitaxel) treatment in patients with angiosarcoma who have not been treated with paclitaxel chemotherapy alone.

Status: Recruiting

Official Title: A Multi-Center Phase III, Randomized, Open-Label Trial of Vigil (BI-SHRNAFURIN  and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Combination with Irinotecan and Temozolomide as a Second-Line Regimen for Ewing’s Sarcoma

Study Purpose: To test the safety and efficacy of Vigil is when given with standard chemotherapy. To determine if Vigil given with standard chemotherapy prevents or delays tumor growth or shrinks an existing tumor.

Status: Suspended

Official Title: A Randomized, Double Blind, Placebo controlled, Phase 2 Study of INBRX 109 as Any line Therapy in Conventional Chondrosarcoma

Study Purpose: To evaluate the anticancer efficacy of INBRX-109 in the intention-to-treat population as measured by progression free survival assessed by central independent radiology review comparing INBRX-109 and placebo.

Status: Pending

Official Title: Testing The Safety Of Combining The Investigational Drug, Amg 232, With Standard Of Care Radiation Therapy Prior To Surgery In Soft Tissue Sarcoma

Study Purpose: To test the safety of a study drug called AMG 232 given with radiation in patients with sarcoma prior to surgery.

Status: Recruiting