Cardiovascular

Official Title: Clinical Trial Title    A Study to Evaluate the Safety and Effectiveness of the InnaVasc Arteriovenous Graft for Hemodialysis Access in Patients with End-Stage Renal Disease (InnaVasc)

Study Purpose: This clinical trial is a prospective, multi-center, single-arm study designed to assess the safety and effectiveness of the IG device in subjects with ESRD who require hemodialysis.

Status: Recruiting

Official Title: Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction (LeAAPS) Trial

Study Purpose: To evaluated safety and effectiveness of prophylactic LAAE for the prevention of ischemic stroke or systemic embolism in subjects undergoing cardiac surgery who have risk factors for AF and ischemic stroke

Status: Active, Not Recruiting

Official Title: Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts: the ROMA trial

Study Purpose: It is the first cardiac surgery trial dedicated exclusively to women. Patients will be randomized in a 1:1 fashion. Patients will be randomized to a single arterial graft (SAG) or multiple arterial grafts (MAG).

Status: Recruiting

Official Title: Stimulation Of the Left Ventricular Endocardium for Cardiac Resynchronization Therapy in Non-Responders and Previously Untreatable Patients (SOLVE CRT)

Study Purpose: This study is a prospective, multi-center, randomized, controlled, double blinded, pivotal trial to study the safety and efficacy of the WiSE-CRT System for Cardiac Re-synchronization Therapy.

Status: Active, Not Recruiting

Official Title: Evaluation of inclisiran versus placebo for the prevention of major adverse cardiovascular and limb events in patients undergoing percutaneous coronary intervention or peripheral endovascular intervention.

Study Purpose: The purpose is to demonstrate superiority of inclisiran (LEQVIO) compared to placebo on lowering total (first and subsequent) major adverse cardiovascular and limb events after coronary or peripheral endovascular revascularization.

Status: Recruiting

Official Title: Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

Study Purpose: To evaluate whether zilebesiran versus placebo reduces the risk of CV death, nonfatal MI, nonfatal stroke, or HF events

Status: Available